South African Kanna (Sceletium tortuosum)
Kanna has an incredible scope of human benefits. It supports the reduction of anxious feelings, helping with the overwhelmed or high-load state anxiety that occurs when the brain region known as the amygdala is over-activated. Since anxiety can impair cognitive performance, Kanna helps with focus.
Dosing: Tune the dosage to your needs. Take one gummy (25mg) as the first dose, and observe feelings of well-being, which usually arise within 30 minutes. If you want to experiment with 50 or 75 mg per serving, try that on the next use. No more than 100mg of MZ0 extract (four gummies) per day is recommended. Take as needed, or use a standard 5-day on / 2-day off protocol.
Ingredients: Organic Cane Sugar, Glucose Syrup, Water, Pectin, Natural Flavors, Sceletium Tortuosum extract, Citric Acid, Malic Acid, Valerian root extract, Vegetable Juice (Color), Carnauba Wax, Trisodium Citrate. (Vegan)
Serving size:
1-2 gummies
Method of Action:
Sceletium has a complex chemistry with at least 32 known alkaloids (including a number of terpenes and saponins) isolated from the genus to date. The major components of Kanna are four alkaloids that are known to have active properties:
- Mesembrine (can be fermented to form Δ7-Mesembrenone)* serotonin reuptake inhibitor (SRI)
- Mesembrenone* dual SRI and PDE4 inhibitor
- Mesembrenol
- Tortuosamine
The mood-elevating action of Sceletium is caused by a number of alkaloids, including mesembrine, mesembrenol and tortuosamine which interact with the brain's dopamine and serotonin receptors. Mesembrine is a major alkaloid present in Sceletium. Mesembrine has been demonstrated to be a potent serotonin-uptake inhibitor and serotonin-releasing agent.
The raw herbs vary in alkaloid percentage, ranging from about 0.4% to about 1.6% of dry material, with an average of around 0.8%. This natural variability has led to the development of standardized extracts.
Do not exceed 100mg of MZ0 extract (four gummies) per day. Please do not use Kanna botanical wellness without prior physician approval if you are taking any psychiatric medications, have any liver or cardiac condition, or are pregnant or nursing.
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